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In vitro biosynthesis and substrate tolerance of the plantazolicin family of natural products

Plantazolicin (PZN) is a ribosomally synthesized and post-translationally modified peptide (RiPP) natural product that exhibits extraordinarily narrow-spectrum antibacterial activity towards the causative agent of anthrax, Bacillus anthracis. During PZN biosynthesis, a cyclodehydratase catalyzes cyc...

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Pubblicato in:ACS Chem Biol
Autori principali: Deane, Caitlin D., Burkhart, Brandon J., Blair, Patricia M., Tietz, Jonathan I., Lin, Alice, Mitchell, Douglas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992447/
https://ncbi.nlm.nih.gov/pubmed/27248686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00369
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