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Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin

Peptide antibiotics represent a class of conformationally-constrained natural products of growing pharmaceutical interest. Plantazolicin (PZN) is a linear, polyheterocyclic natural product with highly selective and potent activity against the anthrax-causing bacterium, Bacillus anthracis. The bioact...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Hao, Yue, Blair, Patricia M., Sharma, Abhishek, Mitchell, Douglas A., Nair, Satish K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573583/
https://ncbi.nlm.nih.gov/pubmed/25635336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb501042a
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