Fungal polyketide engineering comes of age

by Agarwal, Vinayak, Moore, Bradley S.
Published 2014

Enzymatic Synthesis of Polybrominated Dioxins from the Marine Environment

by Agarwal, Vinayak, Moore, Bradley S.
Published 2014

Unusual flavoenzyme catalysis in marine bacteria

by Teufel, Robin, Agarwal, Vinayak, Moore, Bradley S.
Published in Curr Opin Chem Biol (2016)

Sulfonation and Glucuronidation of Hydroxylated Bromodiphenyl Ethers in Human Liver

by Cisneros, Katherine V., Agarwal, Vinayak, James, Margaret O.
Published in Chemosphere (2019)

Chemical Ecology of Marine Sponges: New Opportunities through “-Omics”

by Paul, Valerie J, Freeman, Christopher J, Agarwal, Vinayak
Published in Integr Comp Biol (2019)

Structural Basis for Microcin C7 Inactivation by the MccE Acetyltransferase

by Agarwal, Vinayak, Metlitskaya, Anastasiya, Severinov, Konstantin, Nair, Satish K.
Published 2011

Enzymatic Reductive Dehalogenation Controls the Biosynthesis of Marine Bacterial Pyrroles

by El Gamal, Abrahim, Agarwal, Vinayak, Rahman, Imran, Moore, Bradley S.
Published in J Am Chem Soc (2016)

Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein

by Thapa, Hem R., Robbins, John M., Moore, Bradley S., Agarwal, Vinayak
Published in Biochemistry (2019)

Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7

by Agarwal, Vinayak, Tikhonov, Anton, Metlitskaya, Anastasia, Severinov, Konstantin, Nair, Satish K.
Published 2012

Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis

by Agarwal, Vinayak, Lin, Steven, Lukk, Tiit, Nair, Satish K., Cronan, John E.
Published 2012

Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge

by Cantrell, Thomas P., Freeman, Christopher J., Paul, Valerie J., Agarwal, Vinayak, Garg, Neha
Published in J Am Soc Mass Spectrom (2019)

Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors

by Mohanty, Ipsita, Podell, Sheila, Biggs, Jason S., Garg, Neha, Allen, Eric E., Agarwal, Vinayak
Published in Mar Drugs (2020)

Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

by Gonzalez-Gutierrez, Giovanni, Lukk, Tiit, Agarwal, Vinayak, Papke, David, Nair, Satish K., Grosman, Claudio
Published 2012

Chemoenzymatic synthesis of acyl coenzyme A substrates enables in situ labeling of small molecules and proteins

by Agarwal, Vinayak, Diethelm, Stefan, Ray, Lauren, Garg, Neha, Awakawa, Takayoshi, Dorrestein, Pieter C., Moore, Bradley S.
Published in Org Lett (2015)

Genetic and biochemical reconstitution of bromoform biosynthesis in Asparagopsis lends insights into seaweed ROS enzymology

by Thapa, Hem R., Lin, Zhenjian, Yi, Dongqi, Smith, Jennifer E., Schmidt, Eric W., Agarwal, Vinayak
Published in ACS Chem Biol (2020)

Structural and Mechanistic Insights into C-P Bond Hydrolysis by Phosphonoacetate Hydrolase

by Agarwal, Vinayak, Borisova, Svetlana A., Metcalf, William W., van der Donk, Wilfred A., Nair, Satish K.
Published in Chem Biol (2011)

Enzymatic halogenation and dehalogenation reactions: pervasive and mechanistically diverse

by Agarwal, Vinayak, Miles, Zachary D., Winter, Jaclyn M., Eustáquio, Alessandra S., El Gamal, Abrahim A., Moore, Bradley S.
Published in Chem Rev (2017)

Pangenomic comparison of globally distributed Poribacteria associated with sponge hosts and marine particles

by Podell, Sheila, Blanton, Jessica M., Neu, Alexander, Agarwal, Vinayak, Biggs, Jason S., Moore, Bradley S., Allen, Eric E.
Published in ISME J (2018)

Precursor-guided mining of marine sponge metabolomes lends insight into biosynthesis of pyrrole-imidazole alkaloids

by Mohanty, Ipsita, Moore, Samuel G., Yi, Dongqi, Biggs, Jason S., Gaul, David A., Garg, Neha, Agarwal, Vinayak
Published in ACS Chem Biol (2020)

The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes

by Estrada, Paola, Manandhar, Miglena, Dong, Shi-Hui, Deveryshetty, Jaigeeth, Agarwal, Vinayak, Cronan, John E, Nair, Satish K
Published in Nat Chem Biol (2017)