Inducible Overexpression of GLUT1 Prevents Mitochondrial Dysfunction and Attenuates Structural Remodeling in Pressure Overload but Does Not Prevent Left Ventricular Dysfunction

BACKGROUND: Increased glucose transporter 1 (GLUT1) expression and glucose utilization that accompany pressure overload‐induced hypertrophy (POH) are believed to be cardioprotective. Moreover, it has been shown that lifelong transgenic overexpression of GLUT1 in the heart prevents cardiac dysfunctio...

Full description

Saved in:
Bibliographic Details
Main Authors: Pereira, Renata O., Wende, Adam R., Olsen, Curtis, Soto, Jamie, Rawlings, Tenley, Zhu, Yi, Anderson, Steven M., Dale Abel, E.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835233/
https://ncbi.nlm.nih.gov/pubmed/24052497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000301
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items