ROS1 Immunohistochemistry for Detection of ROS1-Rearranged Lung Adenocarcinomas

ROS1 gene rearrangements are reported in 1–2% of lung adenocarcinomas (ACA) and are associated with response to the multitargeted tyrosine kinase inhibitor, crizotinib. ROS1 rearrangements can be detected using fluorescence in situ hybridization (FISH) however immunohistochemistry (IHC) for ROS1 pro...

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Hlavní autoři: Sholl, Lynette M., Sun, Heather, Butaney, Mohit, Zhang, Chengsheng, Lee, Charles, Jänne, Pasi A., Rodig, Scott J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831351/
https://ncbi.nlm.nih.gov/pubmed/23887156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3182960fa7
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