ROS1 Immunohistochemistry for Detection of ROS1-Rearranged Lung Adenocarcinomas

ROS1 gene rearrangements are reported in 1–2% of lung adenocarcinomas (ACA) and are associated with response to the multitargeted tyrosine kinase inhibitor, crizotinib. ROS1 rearrangements can be detected using fluorescence in situ hybridization (FISH) however immunohistochemistry (IHC) for ROS1 pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Sholl, Lynette M., Sun, Heather, Butaney, Mohit, Zhang, Chengsheng, Lee, Charles, Jänne, Pasi A., Rodig, Scott J.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831351/
https://ncbi.nlm.nih.gov/pubmed/23887156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3182960fa7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items