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Combined Use of ALK Immunohistochemistry and FISH for Optimal Detection of ALK- Rearranged Lung Adenocarcinomas

INTRODUCTION: ALK gene rearrangements occur in ~5% of lung adenocarcinomas (ACA), leading to ALK overexpression and predicting response to targeted therapy. Fluorescence in situ hybridization (FISH) is the gold standard for detection of ALK rearrangements in lung ACA but requires specialized equipme...

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書誌詳細
主要な著者: Sholl, Lynette M., Weremowicz, Stanislawa, Gray, Stacy W., Wong, Kwok-Kin, Chirieac, Lucian R., Lindeman, Neal I., Hornick, Jason L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573350/
https://ncbi.nlm.nih.gov/pubmed/23407557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31827db604
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