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Brief report: Clinical implications of variant ALK FISH rearrangement patterns

INTRODUCTION: Break-apart fluorescence in situ hybridization (FISH) is the FDA-approved assay for detecting anaplastic lymphoma kinase (ALK) rearrangements in non-small cell lung cancer (NSCLC), identifying patients who can gain dramatic benefit from ALK kinase inhibitors. Assay interpretation can b...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Gao, Xin, Sholl, Lynette M., Nishino, Mizuki, Heng, Jennifer, Jänne, Pasi A., Oxnard, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634010/
https://ncbi.nlm.nih.gov/pubmed/26536196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000665
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