Screening of ROS1 Rearrangements in Lung Adenocarcinoma by Immunohistochemistry and Comparison with ALK Rearrangements

ROS1 rearrangement is a predictive biomarker for response to the tyrosine kinase inhibitor, crizotinib. We investigated the usefulness of ROS1 immunohistochemistry (IHC) for the detection of patients who harbor ROS1 rearrangements in two separate cohorts. We also compared ROS1 IHC with ALK IHC in te...

Full description

Saved in:
Bibliographic Details
Main Authors: Cha, Yoon Jin, Lee, Jae Seok, Kim, Hye Ryun, Lim, Sun Min, Cho, Byoung Chul, Lee, Chang Young, Shim, Hyo Sup
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109990/
https://ncbi.nlm.nih.gov/pubmed/25058391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103333
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items