Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.

In Alzheimer disease (AD) the microtubule-associated protein tau is redistributed exponentially into paired helical filaments (PHFs) forming neurofibrillary tangles, which correlate with pyramidal cell destruction and dementia. Amorphous neuronal deposits and PHFs in AD are characterized by aggregat...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Wischik, C M, Edwards, P C, Lai, R Y, Roth, M, Harrington, C R
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 1996
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.11213
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!