Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.

In Alzheimer disease (AD) the microtubule-associated protein tau is redistributed exponentially into paired helical filaments (PHFs) forming neurofibrillary tangles, which correlate with pyramidal cell destruction and dementia. Amorphous neuronal deposits and PHFs in AD are characterized by aggregat...

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Publikašuvnnas:	Proc Natl Acad Sci U S A
Váldodahkkit:	Wischik, C M, Edwards, P C, Lai, R Y, Roth, M, Harrington, C R
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	National Academy of Sciences 1996
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38310/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.11213
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