Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

The unfolded protein response (UPR) is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The role of the UPR during leukemogenesis is unknown so far. Here, we studied the induction of mediators of the UPR in leukaemic cells of AML patients. Increased expressi...

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Hlavní autoři: Schardt, Julian A, Eyholzer, Marianne, Timchenko, Nikolai A, Mueller, Beatrice U, Pabst, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829017/
https://ncbi.nlm.nih.gov/pubmed/19659458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00870.x
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