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Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

The unfolded protein response (UPR) is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The role of the UPR during leukemogenesis is unknown so far. Here, we studied the induction of mediators of the UPR in leukaemic cells of AML patients. Increased expressi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Schardt, Julian A, Eyholzer, Marianne, Timchenko, Nikolai A, Mueller, Beatrice U, Pabst, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829017/
https://ncbi.nlm.nih.gov/pubmed/19659458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00870.x
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