Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

The unfolded protein response (UPR) is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The role of the UPR during leukemogenesis is unknown so far. Here, we studied the induction of mediators of the UPR in leukaemic cells of AML patients. Increased expressi...

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Bibliografiske detaljer
Main Authors: Schardt, Julian A, Eyholzer, Marianne, Timchenko, Nikolai A, Mueller, Beatrice U, Pabst, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829017/
https://ncbi.nlm.nih.gov/pubmed/19659458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00870.x
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