Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange Mass Spectrometry

AMP-Activated protein kinase (AMPK) monitors cellular energy, regulates genes involved in ATP synthesis and consumption, and is allosterically activated by nucleotides and synthetic ligands. Analysis of the intact enzyme by hydrogen/deuterium exchange mass spectrometry reveals conformational perturb...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Landgraf, Rachelle R., Goswami, Devrishi, Rajamohan, Francis, Harris, Melissa S., Calabrese, Matthew, Hoth, Lise R., Magyar, Rachelle, Pascal, Bruce D., Chalmers, Michael J., Busby, Scott A., Kurumbail, Ravi, Griffin, Patrick R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825792/
https://ncbi.nlm.nih.gov/pubmed/24076403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.023
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