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Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange Mass Spectrometry

AMP-Activated protein kinase (AMPK) monitors cellular energy, regulates genes involved in ATP synthesis and consumption, and is allosterically activated by nucleotides and synthetic ligands. Analysis of the intact enzyme by hydrogen/deuterium exchange mass spectrometry reveals conformational perturb...

詳細記述

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書誌詳細
主要な著者: Landgraf, Rachelle R., Goswami, Devrishi, Rajamohan, Francis, Harris, Melissa S., Calabrese, Matthew, Hoth, Lise R., Magyar, Rachelle, Pascal, Bruce D., Chalmers, Michael J., Busby, Scott A., Kurumbail, Ravi, Griffin, Patrick R.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825792/
https://ncbi.nlm.nih.gov/pubmed/24076403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.023
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