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Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange Mass Spectrometry
AMP-Activated protein kinase (AMPK) monitors cellular energy, regulates genes involved in ATP synthesis and consumption, and is allosterically activated by nucleotides and synthetic ligands. Analysis of the intact enzyme by hydrogen/deuterium exchange mass spectrometry reveals conformational perturb...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825792/ https://ncbi.nlm.nih.gov/pubmed/24076403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.08.023 |
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