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Adrenaline-activated structure of the β(2)-adrenoceptor stabilized by an engineered nanobody
G protein-coupled receptors (GPCRs) are integral membrane proteins that play an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. Thus far, it has not been possible to capture...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822040/ https://ncbi.nlm.nih.gov/pubmed/24056936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12572 |
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