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Nanobody stabilization of G protein coupled receptor conformational states

Remarkable progress has been made in the field of G protein coupled receptor (GPCR) structural biology during the past four years. Several obstacles to generating diffraction quality crystals of GPCRs have been overcome by combining innovative methods ranging from protein engineering to lipid-based...

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Detalhes bibliográficos
Main Authors: Steyaert, Jan, K Kobilka, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166880/
https://ncbi.nlm.nih.gov/pubmed/21782416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.06.011
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