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Conformational Dynamics of Single G Protein-Coupled Receptors in Solution

G Protein-Coupled Receptors (GPCRs) comprise a large family of seven-helix transmembrane proteins which regulate cellular signaling by sensing light, ligands, and binding proteins. The GPCR activation process, however, is not a simple on-off switch; current models suggest a complex conformational la...

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Hlavní autoři: Bockenhauer, Samuel, Fürstenberg, Alexandre, Yao, Xiao Jie, Kobilka, Brian K., Moerner, W. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213290/
https://ncbi.nlm.nih.gov/pubmed/21928818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp204843r
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