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Nanobodies to Study G Protein-Coupled Receptor Structure and Function

Ligand-induced activation of G protein-coupled receptors (GPCRs) is a key mechanism permitting communication between cells and organs. Enormous progress has recently elucidated the structural and dynamic features of GPCR transmembrane signaling. Nanobodies, the recombinant antigen-binding fragments...

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Detalles Bibliográficos
Publicado en:Annu Rev Pharmacol Toxicol
Main Authors: Manglik, Aashish, Kobilka, Brian K., Steyaert, Jan
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500200/
https://ncbi.nlm.nih.gov/pubmed/27959623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010716-104710
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