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Nanobodies to Study G Protein-Coupled Receptor Structure and Function

Ligand-induced activation of G protein-coupled receptors (GPCRs) is a key mechanism permitting communication between cells and organs. Enormous progress has recently elucidated the structural and dynamic features of GPCR transmembrane signaling. Nanobodies, the recombinant antigen-binding fragments...

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Bibliografiska uppgifter
I publikationen:Annu Rev Pharmacol Toxicol
Huvudupphovsmän: Manglik, Aashish, Kobilka, Brian K., Steyaert, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500200/
https://ncbi.nlm.nih.gov/pubmed/27959623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010716-104710
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