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Applications of molecular replacement to G protein-coupled receptors

G protein-coupled receptors (GPCRs) are a large class of integral membrane proteins involved in regulating virtually every aspect of human physiology. Despite their profound importance in human health and disease, structural information regarding GPCRs has been extremely limited until recently. With...

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Detalhes bibliográficos
Main Authors: Kruse, Andrew C., Manglik, Aashish, Kobilka, Brian K., Weis, William I.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817703/
https://ncbi.nlm.nih.gov/pubmed/24189241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744491301322X
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