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Structural insights into G-protein-coupled receptor activation
G-protein-coupled receptors (GPCRs) are the largest family of eukaryotic plasma membrane receptors, and are responsible for the majority of cellular responses to external signals. GPCRs share a common architecture comprising seven transmembrane (TM) helices. Binding of an activating ligand enables t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019673/ https://ncbi.nlm.nih.gov/pubmed/18957321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.09.010 |
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