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Structural insights into G-protein-coupled receptor activation

G-protein-coupled receptors (GPCRs) are the largest family of eukaryotic plasma membrane receptors, and are responsible for the majority of cellular responses to external signals. GPCRs share a common architecture comprising seven transmembrane (TM) helices. Binding of an activating ligand enables t...

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Bibliografische gegevens
Hoofdauteurs: Weis, William I, Kobilka, Brian K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019673/
https://ncbi.nlm.nih.gov/pubmed/18957321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.09.010
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