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The role of protein dynamics in GPCR function: insights from the β(2)AR and rhodopsin

G protein-coupled receptors (GPCRs) are versatile signaling proteins that mediate complex cellular responses to hormones and neurotransmitters. Recent advances in GPCR crystallography have provided inactive and active state structures for rhodopsin and the β(2) adrenergic receptor (β(2)AR). Although...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Manglik, Aashish, Kobilka, Brian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986065/
https://ncbi.nlm.nih.gov/pubmed/24534489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2014.01.008
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