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The role of protein dynamics in GPCR function: insights from the β(2)AR and rhodopsin
G protein-coupled receptors (GPCRs) are versatile signaling proteins that mediate complex cellular responses to hormones and neurotransmitters. Recent advances in GPCR crystallography have provided inactive and active state structures for rhodopsin and the β(2) adrenergic receptor (β(2)AR). Although...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986065/ https://ncbi.nlm.nih.gov/pubmed/24534489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2014.01.008 |
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