Structural insights into the dynamic process of β(2)-adrenergic receptor signaling

G protein-coupled receptors (GPCRs) transduce signals from the extracellular environment to intracellular proteins. To gain structural insight into the regulation of receptor cytoplasmic conformations by extracellular ligands during signaling, we examine the structural dynamics of the cytoplasmic do...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Manglik, Aashish, Kim, Tae Hun, Masureel, Matthieu, Altenbach, Christian, Yang, Zhongyu, Hilger, Daniel, Lerch, Michael T., Kobilka, Tong Sun, Thian, Foon Sun, Hubbell, Wayne L., Prosser, R. Scott, Kobilka, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441853/
https://ncbi.nlm.nih.gov/pubmed/25981665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.043
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