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Energy landscapes as a tool to integrate GPCR structure, dynamics and function

G protein coupled receptors (GPCRs) are versatile signaling molecules that mediate the majority of physiologic responses to hormones and neurotransmitters. Recent high-resolution structural insights into GPCR structure and dynamics are beginning to shed light on the molecular basis of this versatili...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deupi, Xavier, Kobilka, Brian K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056154/
https://ncbi.nlm.nih.gov/pubmed/20940434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00002.2010
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