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The role of structure, energy landscape, dynamics, and allostery in the enzymatic function of myoglobin

The grail of protein science is the connection between structure and function. For myoglobin (Mb) this goal is close. Described as only a passive dioxygen storage protein in texts, we argue here that Mb is actually an allosteric enzyme that can catalyze reactions among small molecules. Studies of th...

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Detalhes bibliográficos
Main Authors: Frauenfelder, Hans, McMahon, Benjamin H., Austin, Robert H., Chu, Kelvin, Groves, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30145/
https://ncbi.nlm.nih.gov/pubmed/11226246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041614298
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