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Structural Determinants of Tau Aggregation Inhibitor Potency
Small-molecule Tau aggregation inhibitors are under investigation as potential therapeutic agents against Alzheimer disease. Many such inhibitors have been identified in vitro, but their potency-driving features, and their molecular targets in the Tau aggregation pathway, have resisted identificatio...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820892/ https://ncbi.nlm.nih.gov/pubmed/24072703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503474 |
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