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Pseudophosphorylation of tau protein directly modulates its aggregation kinetics

Hyperphosphorylation of tau protein is associated with neurofibrillary lesion formation in Alzheimer’s disease and other tauopathic neurodegenerative diseases. It fosters lesion formation by increasing the concentration of free tau available for aggregation and by directly modulating the tau aggrega...

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Detalhes bibliográficos
Main Authors: Chang, Edward, Kim, Sohee, Schafer, Kelsey N., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018534/
https://ncbi.nlm.nih.gov/pubmed/20974297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.10.005
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