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Pseudophosphorylation of tau protein directly modulates its aggregation kinetics
Hyperphosphorylation of tau protein is associated with neurofibrillary lesion formation in Alzheimer’s disease and other tauopathic neurodegenerative diseases. It fosters lesion formation by increasing the concentration of free tau available for aggregation and by directly modulating the tau aggrega...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018534/ https://ncbi.nlm.nih.gov/pubmed/20974297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.10.005 |
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