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Structure and mechanism of action of tau aggregation inhibitors

Since the discovery of phenothiazines as tau protein aggregation inhibitors, many additional small molecule inhibitors of diverse chemotype have been discovered and characterized in biological model systems. Although direct inhibition of tau aggregation has shown promise as a potential treatment str...

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Detalhes bibliográficos
Publicado no:Curr Alzheimer Res
Main Authors: Cisek, Katryna, Cooper, Grace L., Huseby, Carol J., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289634/
https://ncbi.nlm.nih.gov/pubmed/25387336
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