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The role of annealing and fragmentation in human tau aggregation dynamics
Alzheimer's disease pathogenesis is associated with the conversion of monomeric tau protein into filamentous aggregates. Because both toxicity and prion-like spread of pathogenic tau depend in part on aggregate size, the processes that underlie filament formation and size distribution are of sp...
Guardat en:
| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442056/ https://ncbi.nlm.nih.gov/pubmed/30745358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006943 |
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