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Tau aggregation and toxicity in tauopathic neurodegenerative diseases

Since its discovery as a structural component of neurofibrillary lesions of Alzheimer's disease more than twenty years ago, tau protein has been implicated in the cascade of events associated with neurodegeneration. Specifically, the “tau hypothesis” posits that misfunction of tau, which occurs...

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Autores principales: Honson, Nicolette S., Kuret, Jeff
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748882/
https://ncbi.nlm.nih.gov/pubmed/18688092
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