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Tau aggregation and toxicity in tauopathic neurodegenerative diseases

Since its discovery as a structural component of neurofibrillary lesions of Alzheimer's disease more than twenty years ago, tau protein has been implicated in the cascade of events associated with neurodegeneration. Specifically, the “tau hypothesis” posits that misfunction of tau, which occurs...

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Bibliografiske detaljer
Main Authors: Honson, Nicolette S., Kuret, Jeff
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748882/
https://ncbi.nlm.nih.gov/pubmed/18688092
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