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Tau aggregation and toxicity in tauopathic neurodegenerative diseases

Since its discovery as a structural component of neurofibrillary lesions of Alzheimer's disease more than twenty years ago, tau protein has been implicated in the cascade of events associated with neurodegeneration. Specifically, the “tau hypothesis” posits that misfunction of tau, which occurs...

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Detalhes bibliográficos
Main Authors: Honson, Nicolette S., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748882/
https://ncbi.nlm.nih.gov/pubmed/18688092
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