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QSAR studies for prediction of cross-β sheet aggregate binding affinity and selectivity
Protein aggregates that accumulate in neurodegenerative diseases are important targets of radiotracer discovery efforts. Although multiple scaffold classes have been reported to bind cross-beta sheet structure, their mechanism of binding and their ability to interact selectively with aggregates of v...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276690/ https://ncbi.nlm.nih.gov/pubmed/22285571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.12.062 |
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