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Potency of a tau fibrillization inhibitor is influenced by its aggregation state
Tau fibrillization is a potential therapeutic target for Alzheimer’s and other neurodegenerative diseases. Several small molecule inhibitors of tau aggregation have been developed for this purpose. One of them, 3,3′-bis(β-hydroxyethyl)-9-ethyl-5,5′-dimethoxythiacarbocyanine iodide (N744), is a catio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2048980/ https://ncbi.nlm.nih.gov/pubmed/17559794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.05.004 |
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