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Tau Isoform Composition Influences Rate and Extent of Filament Formation

The risk of developing tauopathic neurodegenerative disease depends in part on the levels and composition of six naturally occurring Tau isoforms in human brain. These proteins, which form filamentous aggregates in disease, vary only by the presence or absence of three inserts encoded by alternative...

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Bibliografski detalji
Glavni autori: Zhong, Qi, Congdon, Erin E., Nagaraja, Haikady N., Kuret, Jeff
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370253/
https://ncbi.nlm.nih.gov/pubmed/22539343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364067
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