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Tau Isoform Composition Influences Rate and Extent of Filament Formation

The risk of developing tauopathic neurodegenerative disease depends in part on the levels and composition of six naturally occurring Tau isoforms in human brain. These proteins, which form filamentous aggregates in disease, vary only by the presence or absence of three inserts encoded by alternative...

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Bibliografiset tiedot
Päätekijät: Zhong, Qi, Congdon, Erin E., Nagaraja, Haikady N., Kuret, Jeff
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370253/
https://ncbi.nlm.nih.gov/pubmed/22539343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364067
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