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Tau Isoform Composition Influences Rate and Extent of Filament Formation
The risk of developing tauopathic neurodegenerative disease depends in part on the levels and composition of six naturally occurring Tau isoforms in human brain. These proteins, which form filamentous aggregates in disease, vary only by the presence or absence of three inserts encoded by alternative...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370253/ https://ncbi.nlm.nih.gov/pubmed/22539343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364067 |
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