The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair

SUMO conjugation is known to occur in response to double-stranded DNA breaks in mammalian cells, but whether SUMO deconjugation has a role remains unclear. Here, we show that the SUMO/Sentrin/Smt3-specific peptidase, SENP7, interacts with the chromatin repressive KRAB-associated protein 1 (KAP1) thr...

詳細記述

保存先:
書誌詳細
主要な著者: Garvin, Alexander J, Densham, Ruth M, Blair-Reid, Sarah A, Pratt, Kenny M, Stone, Helen R, Weekes, Daniel, Lawrence, Kirsty J, Morris, Joanna R
フォーマット: Artigo
言語:Inglês
出版事項: European Molecular Biology Organization 2013
主題:
Scientific Reports
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818072/
https://ncbi.nlm.nih.gov/pubmed/24018422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.141
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料