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cAMP-responsive Element Modulator α (CREMα) trans-Represses the Transmembrane Glycoprotein CD8 and Contributes to the Generation of CD3(+)CD4(−)CD8(−) T Cells in Health and Disease
T cell receptor-αβ(+) CD3(+)CD4(−)CD8(−) “double-negative” T cells are expanded in the peripheral blood of patients with systemic lupus erythematosus and autoimmune lymphoproliferative syndrome. In both disorders, double-negative T cells infiltrate tissues, induce immunoglobulin production, and secr...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814780/ https://ncbi.nlm.nih.gov/pubmed/24047902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508655 |
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