cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE)

The proinflammatory cytokines IL-17A and IL-17F are primarily produced by Th17 lymphocytes. Both are involved in host defense mechanisms against bacterial and fungal pathogens and contribute to the development of various autoimmune diseases. T lymphocytes from patients with systemic lupus erythemato...

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Autors principals: Hedrich, Christian M., Rauen, Thomas, Kis-Toth, Katalin, Kyttaris, Vasileios C., Tsokos, George C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281648/
https://ncbi.nlm.nih.gov/pubmed/22184122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323261
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