cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE)

Notch signaling constitutes an evolutionarily conserved pathway that transduces signals between neighboring cells and determines major decisions in cell proliferation, survival, and differentiation. Notch signaling has been shown to play a pivotal role during T cell lineage determination. T lymphocy...

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Detalhes bibliográficos
Main Authors: Rauen, Thomas, Grammatikos, Alexandros P., Hedrich, Christian M., Floege, Jürgen, Tenbrock, Klaus, Ohl, Kim, Kyttaris, Vasileios C., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522254/
https://ncbi.nlm.nih.gov/pubmed/23124208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425371
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