cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE)

Notch signaling constitutes an evolutionarily conserved pathway that transduces signals between neighboring cells and determines major decisions in cell proliferation, survival, and differentiation. Notch signaling has been shown to play a pivotal role during T cell lineage determination. T lymphocy...

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Autors principals: Rauen, Thomas, Grammatikos, Alexandros P., Hedrich, Christian M., Floege, Jürgen, Tenbrock, Klaus, Ohl, Kim, Kyttaris, Vasileios C., Tsokos, George C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522254/
https://ncbi.nlm.nih.gov/pubmed/23124208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425371
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