cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE)

Notch signaling constitutes an evolutionarily conserved pathway that transduces signals between neighboring cells and determines major decisions in cell proliferation, survival, and differentiation. Notch signaling has been shown to play a pivotal role during T cell lineage determination. T lymphocy...

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Hlavní autoři: Rauen, Thomas, Grammatikos, Alexandros P., Hedrich, Christian M., Floege, Jürgen, Tenbrock, Klaus, Ohl, Kim, Kyttaris, Vasileios C., Tsokos, George C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522254/
https://ncbi.nlm.nih.gov/pubmed/23124208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425371
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