cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE)

Notch signaling constitutes an evolutionarily conserved pathway that transduces signals between neighboring cells and determines major decisions in cell proliferation, survival, and differentiation. Notch signaling has been shown to play a pivotal role during T cell lineage determination. T lymphocy...

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Autori principali: Rauen, Thomas, Grammatikos, Alexandros P., Hedrich, Christian M., Floege, Jürgen, Tenbrock, Klaus, Ohl, Kim, Kyttaris, Vasileios C., Tsokos, George C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522254/
https://ncbi.nlm.nih.gov/pubmed/23124208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.425371
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