cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus

Appropriate expression of IL-2 plays a central role during the priming and differentiation of T cells. A tight balance between IL-2 and the effector cytokine IL-17A is essential for immune homeostasis. Epigenetic mechanisms have been documented as a key component of cytokine regulation during lineag...

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Detalhes bibliográficos
Main Authors: Hedrich, Christian M., Crispin, Jose C., Rauen, Thomas, Ioannidis, Christina, Apostolidis, Sokratis A., Lo, Mindy S., Kyttaris, Vasileios C., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478624/
https://ncbi.nlm.nih.gov/pubmed/23019580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210129109
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