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cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus
Appropriate expression of IL-2 plays a central role during the priming and differentiation of T cells. A tight balance between IL-2 and the effector cytokine IL-17A is essential for immune homeostasis. Epigenetic mechanisms have been documented as a key component of cytokine regulation during lineag...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478624/ https://ncbi.nlm.nih.gov/pubmed/23019580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210129109 |
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