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Heritable Custom Genomic Modifications in Caenorhabditis elegans via a CRISPR–Cas9 System
We adapted the CRISPR–Cas9 system for template-mediated repair of targeted double-strand breaks via homologous recombination in Caenorhabditis elegans, enabling customized and efficient genome editing. This system can be used to create specific insertions, deletions, and base pair changes in the ger...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Genetics Society of America
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813848/ https://ncbi.nlm.nih.gov/pubmed/23979579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.156075 |
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