Heritable Custom Genomic Modifications in Caenorhabditis elegans via a CRISPR–Cas9 System

We adapted the CRISPR–Cas9 system for template-mediated repair of targeted double-strand breaks via homologous recombination in Caenorhabditis elegans, enabling customized and efficient genome editing. This system can be used to create specific insertions, deletions, and base pair changes in the ger...

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Detaylı Bibliyografya
Asıl Yazarlar: Tzur, Yonatan B., Friedland, Ari E., Nadarajan, Saravanapriah, Church, George M., Calarco, John A., Colaiácovo, Monica P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2013
Konular:
Notes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813848/
https://ncbi.nlm.nih.gov/pubmed/23979579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.156075
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