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Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells

The adapter molecules SLP-76 and LAT play central roles in T cell activation by recruiting enzymes and other adapters into multiprotein complexes that coordinate highly regulated signal transduction pathways. While many of the associated proteins have been characterized, less is known concerning the...

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Detaylı Bibliyografya
Asıl Yazarlar: Coussens, Nathan P., Hayashi, Ryo, Brown, Patrick H., Balagopalan, Lakshmi, Balbo, Andrea, Akpan, Itoro, Houtman, Jon C. D., Barr, Valarie A., Schuck, Peter, Appella, Ettore, Samelson, Lawrence E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811887/
https://ncbi.nlm.nih.gov/pubmed/23979596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00410-13
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