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SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility
Although adaptor ADAP (FYB) and its binding to SLP-76 has been implicated in TcR-induced “inside-out” signaling for LFA-1 activation in T cells, little is known regarding its role in LFA-1-mediated “outside-in” signaling. In this study, we demonstrate that ADAP and SLP-76-ADAP binding are coupled to...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710989/ https://ncbi.nlm.nih.gov/pubmed/19617540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900510106 |
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