Cooperative interactions at the SLP-76 complex are critical for actin polymerization

T-cell antigen receptor (TCR) engagement induces formation of multi-protein signalling complexes essential for regulating T-cell functions. Generation of a complex of SLP-76, Nck and VAV1 is crucial for regulation of the actin machinery. We define the composition, stoichiometry and specificity of in...

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Detalhes bibliográficos
Main Authors: Barda-Saad, Mira, Shirasu, Naoto, Pauker, Maor H, Hassan, Nirit, Perl, Orly, Balbo, Andrea, Yamaguchi, Hiroshi, Houtman, Jon C D, Appella, Ettore, Schuck, Peter, Samelson, Lawrence E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910278/
https://ncbi.nlm.nih.gov/pubmed/20562827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.133
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